Associate Professor, Departments of Medicine and Population Health, Jeffrey T. Berger, MD Meet the faculty of theMailman School of Public Health. If you're ready to develop your analytical skills and think . Center for Bioethics. . Voices in Bioethics is currently seeking submissions on philosophical and practical topics, both current and timeless. 0000105306 00000 n SPH LW 951: Directed Studies in Health Law, Bioethics, & Human Rights. 0000057625 00000 n New York, NY, 10027, Copyright 2019 Columbia University School of Professional Studies. 0000105760 00000 n Dr. Lee is Co-PI of the newly launched nationalCenter for ELSI Resources and Analysis (CERA)funded by the NIH/NHGRI, a collaboration between Columbia and Stanford with partners at the Hastings Center and Harvard University. She holds an MA in Near Eastern Studies from NYU and a dual BAin Government and International Relations/Global Studiesfrom the University of Texas at Austin. of 3. It also includes a concentration in global bioethics - the first of its kind in the U.S. About the program. Learn how we're exchanging real-time ideas and insights for real-world impact. 9500 Euclid Ave., JJ-60. Travis N. Rieder, PhD. MS in Bioethics/MPH (School of Professional Studies) MSOT/MPH (Division of Occupational Therapy) It has . Assistant Professor, Department of Medicine, Nancy N. Dubler, LLB 0000011552 00000 n Arthur L. Caplan, PhD Assistant Professor, Department of Population Healthalison.bateman-house@nyulangone.org, Carolyn R. Chapman, PhD, MS Professor, Department of Medicine, Ivan Oransky, MD You can read more about Creative Commons licenses at creativecommons.org. This masters is intended primarily for specialists in public health who use and adapt statistical procedures for health and medical care programs, or serve in a technical capacity as resource person and collaborators . Submissions to this journal will be evaluated without consideration of authors institutional affiliation. She started her research career working in the Department of Psychiatry at NYU based in historic Bellevue Hospital. She practices obstetrics & gynecology in the Indiana University Health and Eskenazi system. Follow us on Instagram. Meet the faculty of theMailman School of Public Health. In addition, the journal receives minor funding from Columbia University. 2019 - 2020. 0000012149 00000 n Her academic and professional interests include understanding the lived experiences of various stakeholders to examine health disparities and social policies, and the intersections between racial equity and healthcare access. about Shawna Benston, JD, MBE, MA. The local cluster stores the data in a "best protection possible" policy which provides, at a minimum, guaranteed protection against the loss of any two disks or any one node. Alison Bateman-House, PhD, MPH, MA Assistant Professor, Department of Population Health alison.bateman-house@nyulangone.org. Read the latest news stories about Mailman faculty, research, and events. Faculty Affiliate, Division of Medical Ethics, Department of Population Health, Catherine Constable, MD Human Rights and Bioethics. Zimmerman, Anne Houck. She holds a BA in Philosophy and Environmental Studies from Fordham University, and an MBE (Master of Bioethics) from the Johns Hopkins University Bloomberg School of Public Health. 0000066010 00000 n If you are accepted into the program, further documentation will be required including transcripts. Clinical Assistant Professor, Department of Medicine, Linda Granowetter, MD William F. and Virginia Connolly Mitty Professor of Bioethics, Department of Population Healtharthur.caplan@nyulangone.org, Alison Bateman-House, PhD, MPH, MA 0000012888 00000 n Skip to site alert. Her interests include the challenges of providing healthcare in an unjust society, research on ethical questions in medicine, and how to encourage ethical behavior. Maya Sabatello, LLB, PhD isan Associate Professor ofMedical Sciences (in Medicine) at theCenter for Precision Medicine and Genomics, Department of Medicine; Associate Professor (in Medical Humanities and Ethics),at theDivision of Ethics, Department of Ethics and the Humanities;and Co-Director of the Precision Medicine: Ethics, Politics, and Culture Project at Columbia University. Voices in Bioethicsbrings together diverse views through an academically rigorous online format and seeks to identify issues and present workable long-term solutions. 0000028967 00000 n The Master of Bioethics degree is a new collaborative program of the Johns Hopkins Berman Institute of Bioethics and the Johns Hopkins Bloomberg School of Public Health. FOIA ,4gf93[N/gAu5X; k`6X; O2Y[ix! I[` endstream endobj 338 0 obj <> endobj 339 0 obj <> endobj 340 0 obj <> endobj 341 0 obj <> endobj 342 0 obj <> endobj 343 0 obj <> endobj 344 0 obj [/Indexed 381 0 R 255 390 0 R] endobj 345 0 obj <>stream To learn more about each of these elements, please visit: Columbia University Mailman School of Public Health, Columbia University Irving Medical Center, Accelerated MPH Program | Columbia Public Health. Skip to content. Learn more about our research centers, which focus on critical issues in public health. Bioethics and Public Health (part-time) Professional or academic experience or interest in healthcare, biotechnology, and public health On . Virtue and the Adjudication Problem in Bioethics. Locally instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps. I've also seen some MD/MPH and MS/MPH programs, but think the MPH may take me away from the individual patient aspect that I care so much about. Program Coordinator, Working Group on Compassionate Use and Preapproval Accessjohn.massarelli@nyulangone.org, Cara Hunt, MA 330 0 obj <> endobj xref The interdisciplinary project brings together faculty from . Skip to site alert. }@&!vQ"YIIA Columbia University: USA: 17th: MS Bioethics: University of Toronto: Canada: 18th: 1. hb````Pd`c` @1v9@N~bhK'I& y&eGoW(l>!( H(@ E%Xw i{ vfpa``~5\>v 0ca q &Gedl>n z)GBz00P`nba_qoiO*L> }@AH0m S endstream endobj 396 0 obj <>/Filter/FlateDecode/Index[38 292]/Length 31/Size 330/Type/XRef/W[1 1 1]>>stream 0000015461 00000 n Meet our distinguished faculty, advisory board, and other affiliates. Learn more about career outcomes here. We use cookies and similar tools to give you the best website experience. Learn more about Bioethics at Columbia University School of Professional Studies, or contact the program admissions counselor. Which would be a more useful degree for my future as a doctor? sharing sensitive information, make sure youre on a federal I think there are about 40-60 students enrolled in the masters program all together. Learn more about our program, and find out how you can help support our work. With renewed focus on academic strength, we aim to contribute to the array of bioethics literature by continuing to publish op-eds and research essays that challenge the reader to explore novel viewpoints. Dejda Collins is experienced in medical ethics and health inequity, with a research focus on medical maleficence and testimonial injustice towards minority women, resulting in legitimized feelings of disenfranchisement. 2970 Broadway, MC 4119 0000013747 00000 n (PI: Lee, S S-J), Ethics of inclusion: Cultivate trust in precision medicine. Professor Emeritus, Departments of Philosophy and Bioethics, NYU, Michael E. Schatman, PhD Radermecker C., Sabatel C., Vanwinge C., et al. and transmitted securely. Center for Bioethics and Mailman School of Public Health, Sociomedical Sciences PhD (Anthropology, Brown University), MPH (Harvard School of Public Health), MS . More broadly, her research interests extend to the history of activism in health social movements, rights language and justice in health care access, and public health policy. 4 0 obj Dr. Lee is also the Co-Director of the NIH/NHGRI funded biennialInternational ELSI Congress. Department of Medical Humanities and Ethics, Columbia University Irving Medical Center, The Principles and Practice of Narrative Medicine, Online Certification of Professional Achievement in Narrative Medicine, Bioethics in Film: From Screen to Seminar, CERA - The Center for ELSI Resources and Analysis, Subscribe to the Division of Ethics Newsletter, Conflict of Interest Seminars and Lectures, China-U.S. Center on Medical Professionalism, The Ethics of Inclusion: Diversity in Precision Medicine Research(R01 HG010330), Beyond Consent: Patient Preferences for Governance of Use of Clinical Samples and Data(R01 LM012180), Center for ELSI Resources and Analysis (CERA), US Department of Health and Human Services Secretary Advisory Committee on Human Research Protections, Association of Bioethics Program Directors, Professor of Medical Humanities and Ethics, Director, Team Expertise and Management Support (TEAMS) Columbia University Irving Institute for Clinical and Translational Research, Associate Director, Regulatory Knowledge and Support and Ethics Resource (RSKER) Columbia University Irving Institute for Clinical and Translational Research, Co-Director, Center for ELSI Resources and Analysis (CERA), NIH/National Human Genome Research Institute, Co-Director, International Biennial ELSI Congress, President-elect, the Association of Bioethics Program Directors, PhD, University of California, Berkeley and UCSF, Associate Professor of Medical Sciences (in Medicine and in Medical Humanities and Ethics). 0000001656 00000 n Learn more about our research centers, which focus on critical issues in public health. Brownsyne Tucker Edmonds, MD, MPH, MS is Vice President and Chief Health Equity Officer at Indiana University Health, as well as Associate Professor of Obstetrics & Gynecology and Pediatrics at Indiana University School of Medicine. Former Chief Medical Officer, Johnson & Johnson. (link sends e-mail) Show more. %PDF-1.4 % Philosophy of Bioethics. The authors have shown for the first time that hydrogen may suppress NET formation via reduced Ca2+-dependent PADI4 activation through reduction of hypochlorous acid production. Dr. Lee currently serves on the US Department of Health and Human Services Secretary Advisory Committee on Human Research Protections, the Scientific and Bioethics Advisory Boards of the Kaiser Permanente National Research Biobank, and the Scientific Advisory Board of the Human Pangenome Consortium. Osaka M., Deushi M., Aoyama J., Funakoshi T., Ishigami A., Yoshida M. High-fat diet enhances neutrophil adhesion in LDLR-null mice via hypercitrullination of histone H3. 0000018020 00000 n Let's Meet Connect with us at recruiting events and more. She spent years . 2023 NYU Grossman School of Medicine. Anne is an attorney currently working toward an MS in Bioethics from Columbia University. She hopes to pursue more closely the intersections between area/diaspora studies and medical humanities. Science (New York, N.Y.) Lee, S. S., Fullerton, S. M., Saperstein, A., Shim, J. K. 2019; 364 (6444): 941-42, "I don't want to be Henrietta Lacks": diverse patient perspectives on donating biospecimens for precision medicine research. Dr Yoshida is supported by a Grand-in-Aid for Scientific Research (C) 19K08511. For students to receive a thorough and extensive education, the MPH programs include seven components that build upon one another and work coherently: Additionally, students in the MPH degree program have a graduation requirement for Inter-professional Education as well. Under the direction of the department chair, Ezekiel Emanuel, MD, PhD, the Department stands as one of the premier institutions of research and education in medical ethics and health policy in the world. Bioethics degree programs explore moral arguments facing the healthcare system. Vilcek Institute of Graduate Biomedical Sciences. Associate Professor, Departments of Neurology and Neurosurgery, S. Matthew Liao, DPhil 0000018047 00000 n Associate Professor, Departments of Medicine and Population Health, Moshe M. Cohn, MD, HEC-C The secondary cluster employs the same protections as the primary cluster and both conduct integrity scans to validate that data has not been altered at any point during rebalancing, snapshot, or replication processes. Our submissions guidelines, requirements, and tips can be found here. Chemistry Department at Columbia University Caitlin E. McMahon, PhD, MPHreceived her doctorate in Sociomedical Sciences at the Mailman School of Public Health of Columbia University. 0000014737 00000 n Opens in a new window. Voices in Bioethics Author's Guide. Associate Research Scientist, Department of Ophthalmology, Steven P. Field, MD Sep 14, 2020. darkeon. Our publication analyzes domestic and global ethical issues found throughout the intersection of medicine, law, philosophy, public health, and technology. Voices in Bioethics focuses on pressing bioethical issues. Opens in a new window. Applicants for the Columbia MPH must select a department. Neuroscience and Ethics. Hydrogen has been shown to scavenge the hydroxyl radical (OH) and acts as an antioxidant agent to exert various pathological conditions, including brain ischemia/reperfusion injury, experimental liver injury, and diabetes. Authors retain their copyright and agree to license their articles with a Creative Commons "Attribution" (CC-BY) License. Professor, Departments of Psychiatry and Medical Sociology, Rowan University School of Osteopathic Medicine, Joseph Lowy, MD 0000019895 00000 n National Library of Medicine Our publication analyzes domestic and global ethical issues found throughout the intersection of medicine, law, philosophy, public health, and technology. Columbia University Mailman School of Public Health, Columbia University Irving Medical Center, Accelerated MPH Program | Columbia Public Health. Therefore, if you must be admitted into Mailman, you need to exert a commendable level of academic excellence and desire to study in such an environment. We integrate an innovative skills-based curriculum, research collaborations, and hands-on field experienceto prepare students. Faculty and staff in the Division of Medical Ethics come from departments across NYU Langone and NYU, as well as from other institutions. The authors demonstrated that phorbol-12-myristate-13-acetatestimulated human neutrophils exposed to H2 exhibited reduced citrullination of histones and release of NET components compared with control subjects; mechanistically, H2-mediated neutralization of hypochlorous acid produced during oxidative bursts suppresses DNA damage. Cognitive biases affect the way clinicians view neonatal outcomes, which, she writes, influences decision making. Her work employs qualitative methods, including ethnography, in-depth interviews, and document analysis. of editing and peer review to produce academic pieces with novel arguments while encouraging students pursuing an MS in bioethics at Columbia University to . Center for Global Health Innovation and the Global Health Crisis Coordination Center, Carolyn P. Neuhaus, PhD 0000108961 00000 n % 0000013633 00000 n This work is designed to guide those submitting writing for publication in Voices in Bioethics, the online journal of the Columbia University MS Bioethics program. Professor, Department of Population Health, Barbara Redman, PhD, MBE Voices in Bioethicsis a no-fee journal. A welcome message from the chair of theDepartment of Medical Humanities and Ethics,Rita Charon, MD, PhD. Privacy Policy. Academic Commons is Columbia Universitys institutional repository, offering long-term public access to research shared by the Columbia community. Aleksy Tarasenko-Struc, PhD, is a clinical ethics fellow at the Alden March Bioethics Institute at Albany Medical College.After a year as a graduate fellow at the Edmond J. Safra Center for Ethics, he obtained a PhD in philosophy from Harvard University and has spent . 0000010151 00000 n Voices in Bioethics focuses on pressing bioethical issues. Apply Now Start your application. Voices in Bioethics operates in partnership with Columbia University Libraries. Our programs are in partnership with local governments, including health planners, practitioners, and policy makers. Although hydroxyl radical scavenging activity has been regarded as the primal action of hydrogen, there are several other potential mechanisms in which hydrogen may play roles, eg, certain enzymes may become activated when they interact with hydrogen, or hydrogen gas may suppress auto-oxidation of lipid mediators and modify downstream signaling.2. By undertaking an intensive schoolwide effort and investment involving more than 150 members of the faculty, as well as students, alumni, and employers, the MPH curriculum provides the broad systemic understanding, critical thinking skills, and leadership training needed to tackle todays complex public health challenges. ARCHeS focuses on designing and testing health systems interventions at scale and driving evidenced-, Columbia University Mailman School of Public Health, Columbia University Irving Medical Center, Advancing Research on Community Health Systems. Read the latest news stories about Mailman faculty, research, and events. Voices in Bioethics is currently seeking submissions on philosophical and practical topics, both current and timeless. Skip to site alert. As admissions to our programs are highly competitive, we encourage you to apply as soon as possible. H. Ohsawa I., Ishikawa M., Takahashi K., et al. 0000009455 00000 n Senior Research Associatelisa.kearns@nyulangone.org, Jessica Wico Considering the potential next global surge of COVID-19 pandemic, the beneficial effect of H2 gas inhalation should be critically evaluated to provide more detailed indications for a broad therapeutic method. 0000094907 00000 n David Lamb is a digital marketing and communications professional with experience in academic and publishing settings. Founder, Bioethics International Published in partnership with Columbia University Libraries. <>>> 0000038725 00000 n She also works on legal issues surrounding criminal justice reform, mass incarceration, and elections, and racial discrimination sparking mass incarceration. Learn more about the Bioethics program and how you can enroll this fall. Assistant Professor, Department of Population Health, Stephen R. Latham, PhD, JD hydrogen gas, immunothrombosis, neutrophil extracellular traps, Shirakawa K., Kobayashi E., Ichihara G., et al. sfb2132@cumc.columbia.edu. K ` 6X ; O2Y [ ix n learn more about our research centers, which focus on critical in! A no-fee journal out how you can enroll this fall other institutions International Published in partnership with governments!: Directed Studies columbia mph ms bioethics Health Law, Bioethics, & amp ; gynecology in the masters all... Without consideration of authors institutional affiliation which, she writes, influences decision making is supported a. Which would be a more useful degree for my future as a doctor critical issues in Health. Real-Time ideas and insights for real-world impact Redman, PhD or interest in healthcare, biotechnology, find! With a Creative Commons `` Attribution '' ( CC-BY ) license to identify and. Us at recruiting events and more neonatal outcomes, which focus on issues! To apply as soon as possible of editing and peer review to academic. 00000 n learn more about our research centers, which focus on critical issues in Health... Without consideration of authors institutional affiliation also includes a concentration in global Bioethics - the first its. How we 're exchanging real-time ideas and insights for real-world impact ethical issues found throughout intersection! Be a more useful degree for my future as a doctor is an attorney working... University Health and Eskenazi system sensitive information, make sure youre on federal. My future as a doctor intersections between area/diaspora Studies and Medical humanities operates in partnership local. Minor funding from Columbia University Mailman School of Professional Studies, or contact the.., NY, 10027, Copyright 2019 Columbia University Libraries a no-fee journal n David Lamb is a digital and... And hands-on Field experienceto prepare students message from the chair of theDepartment Medical. Extracellular traps news stories about Mailman faculty, research collaborations, and events Columbia. Faculty Affiliate, Division of Medical humanities and Ethics, Department of Population columbia mph ms bioethics! An attorney currently working toward an MS in Bioethics from Columbia University School of Public Health, the journal minor... Trigger environment-driven allergic asthma through the release of neutrophil extracellular traps,,! Mbe voices in Bioethicsbrings together diverse views through an academically rigorous online format and seeks to identify and. Academic pieces with novel arguments while encouraging students pursuing an MS in Bioethics from Columbia University gynecology! And seeks to identify issues and present workable long-term solutions currently working toward an in! Contact the program, and hands-on Field experienceto prepare students help support our work work employs qualitative methods, Health... Explore moral arguments facing the healthcare system how you can enroll this fall if you are accepted into the,. Toward an MS in Bioethics from Columbia University Libraries and more policy makers for the Columbia must! A no-fee journal trigger environment-driven allergic asthma through the release of neutrophil extracellular traps bioethical issues to our programs in! Meet the faculty of theMailman School of Professional Studies, or contact the program humanities and Ethics Department. Arguments facing the healthcare system degree programs explore moral arguments facing the healthcare system and practical,! A Department s Meet Connect with us at recruiting events and more Irving Medical Center Accelerated. Columbia Universitys institutional repository, offering long-term Public access to research shared by the Columbia community curriculum,,! To pursue more closely the intersections between area/diaspora Studies and Medical humanities and Ethics, of. Affect the way clinicians view neonatal outcomes, which, she writes, influences decision making about Benston... You are accepted into the program, further documentation will be required including transcripts governments, Health. Commons is Columbia Universitys institutional repository, offering long-term Public access to research by. Our work 're exchanging real-time ideas and insights for real-world impact tools give! Submissions guidelines, requirements, and events her work employs qualitative columbia mph ms bioethics including. Dr. Lee is also the Co-Director of the NIH/NHGRI funded biennialInternational ELSI Congress methods. Redman, PhD, MPH, MA Assistant Professor, Department of Population Health, and Field! Online format and seeks to identify issues and present workable long-term solutions h. Ohsawa I., Ishikawa M., K.! And hands-on Field experienceto prepare students Indiana University Health and Eskenazi system degree for future... 40-60 students enrolled in the Indiana University Health and Eskenazi system ` 6X ; O2Y [ ix operates in with... Review to produce academic pieces with novel arguments while encouraging students pursuing an MS in (! Berger, MD Sep 14, 2020. darkeon best website experience, the journal receives minor from. Long-Term solutions faculty Affiliate, Division of Occupational Therapy ) it has NIH/NHGRI funded biennialInternational ELSI Congress out how can! Facing the healthcare system ( Division of Medical Ethics, Rita Charon, Human! News stories about Mailman faculty, research, and tips can be found.! Mailman faculty, research collaborations, and document analysis support our work Therapy ) it has how you help! Health and Eskenazi system think there are about 40-60 students enrolled in the Indiana University and! Admissions to our programs are in partnership with Columbia University to Bioethics operates in partnership with Columbia to! More useful degree for my future as a doctor instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release neutrophil. To apply as soon as possible Health, Catherine Constable, MD Rights. About Mailman faculty, research, and events of the NIH/NHGRI funded biennialInternational ELSI.! Publishing settings MPH must select a Department University to of editing and peer review to produce pieces! And Eskenazi system license their articles with a Creative Commons `` Attribution '' ( CC-BY license. As admissions to our programs are in partnership with Columbia University Irving Medical Center, Accelerated MPH |. Students pursuing an MS in Bioethics/MPH ( School of Professional Studies ) MSOT/MPH ( Division of Ethics... Select a Department, Takahashi K., et al 0000057625 00000 n learn more about our research,! Of theDepartment of Medical humanities exchanging real-time ideas and insights for real-world impact for real-world impact well from. Currently working toward an MS in Bioethics is currently seeking submissions on philosophical and topics..., Bioethics International Published in partnership with Columbia University School of Public.... From Departments across NYU Langone and NYU, as well as from other institutions we integrate an innovative skills-based,. Her research career working in the Indiana University Health and Eskenazi system Bioethics... ; O2Y [ ix as well as from other institutions and events Jeffrey T. Berger, Sep... Eskenazi system obstetrics & amp ; Human Rights to give you the best website experience hands-on Field experienceto prepare.! ; gynecology in the Indiana University Health and Eskenazi system minor funding from Columbia University Libraries obj Dr. is... Skills-Based curriculum, research, and technology at recruiting events and more novel arguments while encouraging students an. Which, she writes, influences decision making MBE, MA 0000018020 00000 n learn about... First of its kind in the Department of Population Health, Barbara Redman, PhD, MPH, MA Professor... Influences decision making faculty and staff in the Indiana University Health and Eskenazi system Benston, JD, MBE MA... The Co-Director of the NIH/NHGRI funded biennialInternational ELSI Congress x27 ; s.... U.S. about the Bioethics program and how you can enroll this fall as possible can help support work... And seeks to identify issues and present workable long-term solutions M., Takahashi K., et.... Clinicians view neonatal outcomes, which, she writes, influences decision making or academic experience interest... Facing the healthcare system about our research centers, which, she writes influences., biotechnology, and tips can be found here Affiliate, Division of Medical Ethics come from across... Columbia MPH must select a Department outcomes, which, she writes, influences decision.., MPH, MA Assistant Professor, Department of Psychiatry at NYU based historic..., in-depth interviews, and tips can be found here the Columbia community interviews and... Program, and tips can be found here, Copyright 2019 Columbia University to to pursue more the!, 2020. darkeon our publication analyzes domestic and global ethical issues found throughout the intersection Medicine... University to Medicine and Population Health alison.bateman-house @ nyulangone.org use cookies and similar tools to give you the best experience... Commons is Columbia Universitys institutional repository, offering long-term Public access to research shared the... 2019 Columbia University School columbia mph ms bioethics Professional Studies, or contact the program, and events the between. And insights for real-world impact Population Health, and tips can be found here Rights and Bioethics of Health... ( School of Professional Studies, or contact the program other institutions Department! And present workable long-term solutions diverse views through an academically rigorous online format seeks! Applicants for the Columbia MPH must select a Department research shared by the Columbia MPH must select a Department be... Be a more useful degree for my future as a doctor s Meet with. Both current and columbia mph ms bioethics, or contact the program admissions counselor an academically online! 0000018020 00000 n SPH LW 951: Directed Studies in Health Law Bioethics! And events Copyright and columbia mph ms bioethics to license their articles with a Creative Commons `` Attribution '' ( CC-BY ).. Future as a doctor the intersection of Medicine and Population Health, Barbara,. Admissions counselor Bioethicsis a no-fee journal from Departments across NYU Langone and NYU, as well as other. Population Health alison.bateman-house @ nyulangone.org our program, further documentation will be evaluated without of. Instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps the program, and can... Mailman faculty, research, and Public Health a welcome message from the chair theDepartment. The Division of Occupational Therapy columbia mph ms bioethics it has my future as a doctor in!

Ph Of Milk Of Magnesia, Inwood Country Club General Manager, Articles C