Some are broad-spectrum, meaning they act on a wide range of disease-causing bacteria. The dose is 600 mg every 12 hours. Food high in tyramine include those that may have undergone protein changes by aging, fermentation, pickling, or smoking to improve flavor, such as aged cheese, fermented or air-dried meats, sauerkraut, soy sauce, tap beers, and red wines. Also, do not use this medicine if you or your child are also using the following medicines: buspirone (Buspar), dobutamine (Dobutrex), dopamine (Intropin), epinephrine (Adrenalin), norepinephrine (Levophed), cold medicines or decongestants (eg, phenylpropanolamine, pseudoephedrine, or Sudafed), medicine to treat depression (eg, amitriptyline, bupropion, doxepin, fluoxetine, nortriptyline, paroxetine, Celexa, Effexor, Elavil, Lexapro, Paxil, or Zoloft), medicine to treat migraine headaches (eg, sumatriptan, zolmitriptan, Axert, Imitrex, or Zomig), or narcotic pain medicines (eg, meperidine, Demerol). Similarly, cocoa contains antioxidant polyphenols that have beneficial prebiotic effects on the gut microbiota. Mayo Clinic does not endorse any of the third party products and services advertised. Gently mix the oral suspension (liquid) by turning the bottle upside down 3 to 5 times. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Avoid marmite. You should not use Zyvox if you are allergic to linezolid. This article explains what you should and shouldnt eat during and after antibiotics. For example, studies have shown that it can be harmful to consume grapefruit and grapefruit juice while taking certain medications, including antibiotics (34, 35). Some medicines can interact with linezolid and cause a serious condition called serotonin syndrome. The amount of medicine that you take depends on the strength of the medicine. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). How Linezolid Tablet works Linezolid 600 Tablet is an antibiotic. When taken with certain foods or drinks, linezolid can cause an increase in blood pressure. This effect can be deadly. Avoid foods that have a high level of tyramine, such as: pickled or fermented meats, smoked or air-dried meats; any meat, cheese, or other protein-based food that has been improperly stored. This medicine may cause a serious reaction called lactic acidosis (build-up of acid in the blood). Zyvox liquid (oral suspension) contains phenylalanine and could be harmful if you have phenylketonuria (PKU). Minimally clinically significant. In fact, Zyvox is an extremely effective antibiotic that is used to cure resistant microbial infections including: There are a few reasons Zyvox isn't widely used: It is important to sparingly use new, effective antibiotics to prevent resistant organisms. A couple studies have shown that cocoa polyphenols also increase healthy Bifidobacteria and Lactobacillus in the gut and reduce some unhealthy bacteria, including Clostridia (32, 33). Email this report to a friend, doctor, or patient, Methicillin-Resistant Staphylococcus Aureus Infection. Before using this medicine, tell your doctor about all other medications you use. The dose of this medicine will be different for different patients. These may be symptoms of hyponatremia (low sodium levels in the blood) or syndrome of inappropriate antidiuretic hormone (SIADH). Many drugs can interact with linezolid, and some drugs should not be used together. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, 6 Minutes of Exercise May Protect Brain From Alzheimer's, 'Disturbing' Rate of Adverse Events During Hospital Stays. Also, do not use this medicine if you or your child are also using the following medicines: buspirone (Buspar), dobutamine (Dobutrex), dopamine (Intropin), epinephrine (Adrenalin), norepinephrine (Levophed), cold medicines or decongestants (eg, phenylpropanolamine, pseudoephedrine, or Sudafed), medicine to treat depression (eg, amitriptyline, bupropion, doxepin, fluoxetine, nortriptyline, paroxetine, Celexa, Effexor, Elavil, Lexapro, Paxil, or Zoloft), medicine to treat migraine headaches (eg, sumatriptan, zolmitriptan, Axert, Imitrex, or Zomig), or narcotic pain medicines (eg, meperidine, Demerol). Some medicines can cause unwanted or dangerous effects when used with Zyvox. Many other medications may also interact with linezolid, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. In turn, this can slow the rate at which medicines are absorbed (29). Do not use linezolid if you have used an MAO inhibitor in the past 14 days. Avoid fava beans, Chinese pea pods and Italian beans. On the flip side, you also need to be careful taking certain vitamins and probiotics with cephalexin, which can block the absorption of the antibiotic. It could be that only foods that are supplemented with high doses of calcium should be avoided when taking antibiotics. Talk with your doctor before using this medicine if you plan to have children. When your doctor prescribes linezolid (Zyvox), she should give you a list of foods to avoid 1. This can be harmful to your health. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking linezolid. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Your doctor will probably tell you not to take linezolid if you are taking one or more of these medications, or have taken them within the past two weeks. Avoid overripe bananas and any dish cooked with banana with the peels still on. Limit foods high in tryptophan at one meal. Take linezolid until you finish the prescription, even if you feel better. 2. Your doctor may order certain blood tests to check your body's response to linezolid. Select a condition to view a list of medication options. Although some studies support the use of ginger for stomach pain, more research needs to be done to determine whether it is effective. "The gastrointestinal barrier and the gut immune system undergo several changes from both the antibiotic and the infection," she said . A dangerous drug interaction could occur. This medicine may cause serious condition called serotonin syndrome when taken with certain medicines, including medicines to treat depression (SSRIs) or narcotic pain medicines. Copyright 2023 Leaf Group Ltd., all rights reserved. It is used to treat infections of the lungs (pneumonia), skin, and soft tissues. Avoid liver, pate and game meats, which tend to be mishandled. Taking probiotics during and after a course of antibiotics can help reduce the risk of diarrhea and restore your gut microbiota to a healthy state. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Can I Take Vitamins If I Am Taking Antibiotics? Thyroid problemsShould not be used in patients with these conditions unless they are closely monitored by their doctor for hypertension and serotonin syndrome. While taking linezolid, avoid very ripe fruit as well as unpasteurized juice, bananas, raspberries, canned figs and dried fruit. Fermented foods are produced by microbes and include yogurt, cheese, sauerkraut, kombucha and kimchi, among others. If you have any questions or if mild diarrhea continues or gets worse, check with your doctor. Mineral vitamins in particular get a red . This medicine may cause diarrhea, and in some cases it can be severe. If this occurs, there are certain precautions your doctor may ask you to take, especially when your blood count is low, to reduce the risk of infection or bleeding: This medicine may cause infertility to men. If taking probiotics after antibiotics, it may be better to take one that contains a mixture of different species of probiotics, rather than just one. You may feel weak, drowsy, confused, anxious, or very hungry. Generic name: linezolid (oral/injection) [lin-EZ-oh-lid] There are 2 alcohol/food/lifestyle interactions with linezolid. You can take it before, with or after food. Drug information provided by: Merative, Micromedex. 4.9k views Reviewed >2 years ago. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Eating tyramine while you are using linezolid can raise your blood pressure to dangerous levels. Furthermore, the overuse of antibiotics can lead to antibiotic resistance, making them ineffective at killing disease-causing bacteria (11). Highly clinically significant. What should I know about storage and disposal of this medication? Using this medicine with any of the following medicines is not recommended. Other studies have also found that fermented foods may be beneficial during antibiotic treatment. While many foods are beneficial during and after antibiotics, some should be avoided. Avoid vitamin supplements containing yeast. Some things that can lead to low blood sugar are exercising more than normal or waiting too long to eat. You may have trouble seeing or have a headache that won't go away. Some things that can lead to low blood sugar are exercising more than normal or waiting too long to eat. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take other medicines unless thy have been discussed with your doctor. Ginseng is usually fermented or pickled and should be avoided. Yet, they can come with some negative side effects. Zyvox pregnancy and breastfeeding warnings, Methicillin-Resistant Staphylococcus Aureus Infection. You may have trouble seeing or have a headache that won't go away. Avoid meat products that have been smoked, dried, marinated or fermented. Tyramine rich foods are recommended to be avoided if you are taking a medication that inhibits MAO, as Zyvox does. numbness or tingling in the hands, feet, or lips, sores, ulcers, or white spots on the lips or in the mouth, vomiting of blood or material that looks like coffee grounds, blistering, peeling, or loosening of the skin, burning, numbness, tingling, or painful sensations, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, weakness in the arms, hands, legs, or feet, Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site, itching of the vagina or outside genitals, thick, white curd-like vaginal discharge without odor or with mild odor. Linzoshine 600 Tablet may be taken with or without food, preferably at a fixed time. I've heard of non-drowsy Benadryl but can't find it anywhere. When protein begins to break down, tyramine is formed, according to the Micromedex database. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. If this occurs, there are certain precautions your doctor may ask you to take, especially when your blood count is low, to reduce the risk of infection or bleeding: This medicine may cause infertility to men. Follow all directions on your prescription label and read all medication guides or instruction sheets. Descriptions Linezolid is used to treat certain bacterial infections in many different parts of the body, including certain types of skin infections or pneumonia. ", Mayo Clinic: "Herbal supplements and heart medicines may not mix", Mayo Clinic: "What are the effects of drinking alcohol while taking antibiotics? Follow your doctor's orders or the directions on the label. Probiotics: Like prebiotics . What special precautions should I follow? Summary: Fermented foods contain healthy bacteria, including Lactobacilli, which can help restore damage to the microbiota caused by antibiotics. This is a decision you and your doctor will make. Avoid yeast and all yeast products including brewer's yeast. Diarrhea may be a sign of a new infection. Many high-fiber foods are prebiotic. Copyright, 2023. This medicine may cause diarrhea, and in some cases it can be severe. Prepare your injection only when you are ready to give it. Zyvox may also be used for purposes not listed in this medication guide. Talk with your doctor before using this medicine if you plan to have children. Check with your doctor right away if blurred vision, difficulty in reading, or any other change in vision occurs during treatment with this medicine. Vancomycin-resistant enterococcal (VRE) infections, MRSE (Methicillin-resistant Staphylococcus aureus). Agree with Dr. F: You may eat sea food as tolerated. How do I take linezolid? Store it at room temperature and away from light and excess heat and moisture (not in the bathroom). Interactions. Do not use if the medicine has particles in it. Take linezolid exactly as directed. See 12 top healthy meal delivery services. They should be eaten after taking antibiotics but not during, as. This medicine is available only with your doctor's prescription. This often takes a lot of the good bacteria with it. Studies have shown that foods that contain dietary fiber are not only able to stimulate the growth of healthy bacteria in the gut, but they may also reduce the growth of some harmful bacteria (26, 27, 28). It is usually taken with or without food twice a day (every 12 hours) for 10 to 28 days. You should not use this medicine at is resistant to medication if you have untreated or uncontrolled high blood pressure, a carcinoid tumor, adrenal gland tumor, or a severely overactive thyroid. Is there such a thing? Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. If your dose is different, do not change it unless your doctor tells you to do so. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Do not shake the suspension. Because there are no studies specifically regarding chocolate and linezolid, ask your doctor for her guidance on consuming chocolate while you are taking linezolid 1. You may feel weak, drowsy, confused, anxious, or very hungry. Others are designed to kill certain species of bacteria. Why Doesn't the U.S. Have at-Home Tests for the Flu? In case of overdose, call the poison control helpline at 1-800-222-1222. Foods that are high in tyramine include, but are not limited to, air dried meats; aged or fermented meats; sausage or salami; pickled herring; anchovies; liver; red wine; beer; aged cheeses, including blue, brick, brie, cheddar, parmesan, romano, and swiss; sour cream; sauerkraut; canned figs; raisins; bananas or avocados (particularly if overripe); soy beans; soy sauce; tofu; miso soup; bean curd; fava beans; or yeast extracts (such as Marmite). To avoid this, do not eat large amounts of foods or drink beverages that have a high tyramine content (most common in foods that are aged, fermented, pickled, or smoked to increase their flavor, including aged cheeses, air-dried, fermented, or smoked fish, meat, or poultry, sauerkraut, soy sauce, red wine, or tap beer). Advertising revenue supports our not-for-profit mission. Portions of this document last updated: March 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/linezolid-oral-route/precautions/drg-20067254. Check with your doctor immediately if you think you or your child are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. This means that the medication could potentially stay in your body for too short, or too long, a time, rendering it either useless, or else potentially lethal. Call your doctor right away if you or your child feel very tired, weak, or nauseated, if you vomit or have trouble breathing, or if you feel lightheaded or fainting. Yogurt may also reduce the risk of antibiotic-associated diarrhea. Some of these have shown that taking either normal or probiotic-supplemented yogurt can reduce diarrhea in people taking antibiotics (23, 24, 25). Ask your doctor for his guidance on eating nuts while you are taking linezolid 1. All rights reserved. The condition is potentially fatal and may cause symptoms such as severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Contact your doctor if you have questions about any foods. This morning after eating oatmeal breakfast I took 2 tablets. Still, people should avoid drinking alcohol while taking metronidazole. I am supposed to take 2 t Can you take Claritin and Zyrtec together? You should avoid the following types of foods: Check with your doctor right away if blurred vision, difficulty in reading, or any other change in vision occurs during treatment with this medicine. This article takes a, What you eat before drinking alcohol can have a huge impact on how you feel at the end of the night and the next morning. An interaction with linezolid could cause a serious condition called serotonin syndrome. Avoid Linezolid 600 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer. vision problems, changes in color vision; severe stomach pain, diarrhea that is watery or bloody; sweating, feeling anxious or shaky (may be signs of low blood sugar); high levels of serotonin in the body - agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea; lactic acidosis - unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired; or. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Avoid eating or drinking large amounts of foods and beverages containing tyramine while taking linezolid. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). You may develop low blood sugar while you or your child are taking this medicine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Available for Android and iOS devices. Avoid foods that have a high level of tyramine, such as: aged cheeses or meats; pickled or fermented meats, smoked or air-dried meats; sauerkraut; soy sauce; tap beer (alcoholic and nonalcoholic); red wine; or CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Do not let anyone else take your medication. Throw away any unused medicine 21 days after it has been prepared. Be sure to mention any of the following: epinephrine (EpiPen); meperidine (Demerol); medications for migraine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), and zolmitriptan (Zomig); phenylpropanolamine (no longer available in the US); and pseudoephedrine (Sudafed; in many cold or decongestant medications). Linezolid is used to treat certain bacterial infections in many different parts of the body, including certain types of skin infections or pneumonia. Replenishing it with healthy yogurts and drinks is a simple home remedy worth trying to see if it helps in your case. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Instead, the best way to dispose of your medication is through a medicine take-back program. When you ingest them, they help to make your gut a friendly place for more healthy bacteria to grow. Therefore, it is best to temporarily avoid high-fiber foods during antibiotic treatment and instead focus on eating them after stopping antibiotics. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Whenever you are prescribed antibiotics especially for high cholesterol, high blood pressure, or heart problems it's best to avoid the citrus fruit altogether for the duration of the prescription, as well as the 24 hours before and after you start your course. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. There are 504 drug interactions with linezolid. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Along the same lines of sparing use due to resistance, Zyvox is very effective but only for certain infections. For example, red wine contains antioxidant polyphenols, which are not digested by human cells but are digested by gut bacteria. Copyright 1996-2023 Cerner Multum, Inc. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. These include cough or cold drugs, diet pills, stimulants, non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, and some natural products or aids. If you have any questions about this, check with your pharmacist. The fiber is digested and fermented by healthy gut bacteria, allowing them to grow (30). However, dietary fiber can slow the rate at which the stomach empties. If you stop taking linezolid too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. Is using both safe? Some studies have shown that changes to the gut microbiota caused by excessive antibiotic use in early life may even increase the risk of weight gain and obesity (10). Avoid kefir, a fermented dairy beverage. Created for people with ongoing healthcare needs but benefits everyone. Contact your doctor right away if you or your child experience agitation, confusion, diarrhea, fever, overactive reflexes, poor coordination, restlessness, shivering, sweating, or trembling or shaking. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Duplication for commercial use must be authorized by ASHP. "Product Information. I have bad allergies! Keep from freezing. Unfortunately, there have been confirmed reports that Zyvox resistant organisms are occurring at various health care locations. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This means it can have an effect that is different to what you expected. Because of this, it is important that you avoid foods that contain tyramine; foods containing tyramine can also elevate your blood pressure, leading to a potentially serious reaction. The average household teaspoon may not hold the right amount of liquid. This medicine may cause serious condition called serotonin syndrome when taken with certain medicines, including medicines to treat depression (SSRIs) or narcotic pain medicines. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. Linezolid can lower the number of white blood cells in your blood temporarily, increasing the chance of getting an infection. Here's Why Thats a Bad Idea, Whole grains (porridge, whole grain bread, brown rice). Ask your doctor before making any changes in how or when you take your medications. The length of your treatment depends on the type of infection you have. Avoid eating foods or beverages with high tyramine content while taking linezolid (Zyvox). Zyvox (linezolid)." If a list of these foods and beverages is not given to you, ask your doctor to provide one. Ask your healthcare professional how you should dispose of any medicine you do not use. rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate). These foods and beverages include alcoholic beverages, especially beer, Chianti, and other red wines; alcohol-free beer; cheeses (especially strong, aged, or processed varieties); sauerkraut; yogurt; raisins; bananas; sour cream; pickled herring; liver (especially chicken liver); dried meats and sausage (including hard salami and pepperoni); canned figs; avocados; soy sauce; turkey; yeast extracts; papaya products (including certain meat tenderizers); fava beans; and broad bean pods. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Usually avoid combinations; use it only under special circumstances. It works by killing bacteria or preventing their growth. Your prescription is probably not refillable. Fiber cant be digested by your body, but it can be digested by your gut bacteria, which helps stimulate their growth. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. You should take it twice a day every 12 hours, for example at 8.00am and 8.00pm. Antibiotics Recommended for Infected Wounds, Stonyfield Organic Probiotic Yogurt Smoothies, The American Council on Science and Health. We comply with the HONcode standard for trustworthy health information. Eating high fiber and prebiotic foods may also help. They'll be able to tell you specific foods to consume, and avoid, based on your particular antibiotic prescription. Copyright: Merative US L.P. 1973, 2023. When you take antibiotics, diarrhea can be a common side effect. For non-prescription products, read the label or package ingredients carefully. Eating tyramine while you are using linezolid can raise your blood pressure to dangerous levels. Infection, Gram-negativeUse is not indicated in patients with this condition. Use Zyvox exactly as prescribed by your doctor. If a list of these foods and beverages is not given to you, ask your doctor to provide one. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.

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