I gave this for the first time to my hound and about 3 hours later, she was very unsteady on her feet, eyes half shut and then had 4 episodes of breathing rapidly that each lasted 30 seconds or so and all happened within a 30 minute period. The company will not cover any products purchased through sites like Chewy or 1-800-Pet-Meds because they cannot be tracked to ensure they're legitimate and properly stored/handled (and due to the company's stance on product diversion). It's getting better and I decided to just wait and hope when this stuff clears out in 30 days he goes back to normal. The results are fatal for fleas and ticks but safe for mammals such as your dog. My miniature Dash hound did not pull out. He seems to be out of sorts, staring into space, getting freaked out when he can't see me (I thought he was losing his eyesight). Did anyone see any signs of improvement in their dogs? As per the vet, Simparica is an excellent flea and tick product that is available in oral form. Her blood work came back fine. The veterinary medicinal product should be administered at a dose of 1.2-2.4 mg/kg of sarolaner, 0.024-0.048 mg/kg of moxidectin and 5-10 mg/kg of pyrantel in accordance with the following table: Bodyweight (kg) Tablet strength 3 mg/0.06 mg/12.5 mg. Tablet strength 6 mg/0.12 mg/25 mg. Tell your veterinarian if your dog has a history of seizures or other neurologic disease. It is the flea and tick component that is the problem. He now cannot go in the car anymore. He is a 89 lbs 5 y/o pitbull who has never had any issues before. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. I rescued a dog that had a light case of heartworms. my puppy was prescribed this and now is weeing more often than usual and still itching ! We are already close to $2000 in Vet bills not counting the poison we bought her. I wish I would have seen this conversation before giving my 8 year old Labrador Retriever his first dose of Simparica Trio on Wednesday March 31st! Be aware! All medicines come with some potential risks and side effects, and pet owners should weigh the potential risks and benefits in consultation with a veterinarian. We go for more bloodwork today and are praying for better news. Plan to take him to see the vet tomorrow. I would say these changes may have happened more suddenly than just normal aging so I'm not going to give him this medication anymore. My lab puppies have been taking Simparica Trio for 2 months. Will be back at PetSmart on Monday. We started the medication on Dec. 1st and 3 days later it started with vomiting and loss of appetite. Simparica may show slide side effects in a few dogs like tremors, unsteadiness, and/or seizures but else it is Tested and FDA approved suits to 90% of dogs. I have always used topical tx. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. I advise all pet owners to know the side effects. Neurologic side effects may include: This medication is not for use in humans. Our dog has had 2 Seizures this month and we are going to stop using Simparica. It will eliminate infestations of deer or black-legged ticks, lone star ticks, Gulf Coast ticks, American dog ticks, and brown dog ticks. Simparica is available by prescription only, so discuss any history your dog has of seizure disorders with your veterinarian when determining the best flea and tick treatment for your pet. About 2 weeks later he had tremors, drooling, lethargic, uncoordinated, vomiting and was touch and go for a couple days. I lost my dog due to Simparica Trio. Is due for another tablet but I have been holding off. Just wanted to share my experience in case anyone else has similar experience with dog's character changing. Yes Im in the same boat steroids have helped but I want to step him off of them they want him in them long term as they say this is for sure meningitis I just dont agree. I hope I have found the culprit to his digression. I quit the canned sweet potatoes (he loved them) thinking it was the syrup, that I drained anyway before adding to mixture. As I said, the first was a week after taking it, then the 2nd and third seizure happened at day 29. Benefits: Each tablet provides a full month of protection against fleas and ticks. I gave my 10 year old Bull Terrier a dose of Simparico Trio Thursday December 3. In a well-controlled laboratory study, SIMPARICA TRIO began to kill fleas at 4 hours and demonstrated 100% effectiveness at 8 hours after initial administration. MONEY!!. Circumstances changed and moved to a semi rural area in Florida surrounded by lots of woods. It was the first time she had taken Simparica. The Maltese mix is lethargic and wont jump on bed or couch. Today started diarrhea & he has gone 5 times so far while not eating much. Stressing out now. The older of the 2 Poodles seemed to do fine but my younger Poodle who was about 3 years old was definitely affected and we had a difficult time even getting him to eat for at least 2 weeks. Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. My chihuahua was given this three weeks back, I actually requested I kept my old treatment but they assured me it was safe and good. I want to cry I wish I could get it out of her system after reading these comments. She had right sided weakness, with right sided neglect( the inability to process stimuli with impaired spatial recognition ). All the swelling went down immediately and the itching went away too. I have noticed that recently he seems to stumble a little from time-to-time. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. I used to use revolution but they dont cover ticks as well. I am devastated. But he had a terrifying seizure when I was out walking him on December 26, 2020 with no previous known history (he is rescue I've had since he was 2). Just wondering? Getting him to go out was nearly impossible. He has been very lethargic, he was an extremely playful pup. I gave my sweet little toy poodle Simpaica today, and one hour later this poor dog went from happy and healthy to having a terrible seizure. I thought maybe it was just a allergy break out which she's never had this long now I'm wondering if she's continuing to have a reaction. Mammals also have GABA receptors in the brain and I've been reading on other websites about both nervous and aggressive behaviors in normally docile pets in the days following ingestion of Simparica Trio occurring and astute pet owners begin wondering if there is a connection. We have an appt for a skin scraping. Any believers out there please say a prayer for our pup as I will for the people on this thread. I wish I read these side effects before my vet recommended Simparica Trio for my 12 week old Bichon. And yeah he ate today 4 chicken breast and appeared to want it even better. She had some itching and a bit lethargic but is eating very well. In a weak moment last week she prescribed Simparica for a flea problem my 5 year old Springer was having. Vets at Petsmart should know better; changing vets. I will not be continuing with this treatment. Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. I feel like she's been an experiment to make others money. The vet office called simparica hotline to find out if it was safe to give her another one. All other pets in the home must also be treated with a flea control product for a minimum of 30 days prior to the report. Charlie took the pill on Monday and could not even walk this morning. He was lethargic & laying in his crate alot . I'll be calling them tomorrow. Bella is very consistent and normally has two bowel movements but hubby noted an increase in bowel movements and their amounts. All they did was give me a pill in a bag with possible side effects of vomiting or diarrhea. Today she has fallen 2 or 3 times in the last 8 hours). If anyone wants to write or call to complain to the company I have all the details. He is acting very skittish/scared like behavior, wants to just lay down. HELP!! Its Sunday night and still vomiting. Never ever again with this med for him. My wife and I didn't understand why. This medicine needs to be stopped. This is lethal medication for dogs and should be taken off the market now. Hope all is well .my dog is 3,ive had him on Simparica trio for about 1.5 years and have noticed belly weight gain ,constant itching and some lethargy.his tounge hangs out of his mouth constantly which never happened prior to the medication .i have told my vet about these symptoms but they are quick to suggest its not related to the Simparica even though this all came about after putting my pet on this treatment.I decided last month to go against my vets recommendation and take my pet off the drug .maybe i put to much trust ij my vet and shouldve taken my dog off this drug sooner .better late then never .anyone suggest a tick and flea treatment less harmful for dogs ?? I am so sorry to all of you and my heart goes out to you and your babies. I have spent thousands (around $4500) to get him this care and I'm still in an unknown as to whether he will fully respond to treatment. No appetite, not like Charlie. Tremors continued, on and off, for 2 hours. Im wondering if anyone else has seen these types of symptoms. Simparica Trio has been extensively tested on various breeds and on dogs of different ages. It may be that he is getting older as he is now one years old and he was neutered about three months ago. Has there been any improvement if so how long after did it take ? Youre an idiot then! I recently switched my 3.5 year old German Shepard to simparica and about 2 weeks after his first dose he had two seizures in one night and has NEVER had them before. I thought it was just her aging but now I think it al started when she started this medication. Simparico Trio, will not be given to my dog ever again. If it was due to the Simparica, then it would expected to be resolved within a day or two. My dog died from it after one dose within 24 hours. None of our pets did they were healthy. . Did you go to the vets or not? Used my own intuition and knowledge to make a good choice for my pet .good luck to everyone one here ! This should be taken off the market-it's just a BIG pharmaceutical moneymaker at the expense of animals and their unsuspecting owners. It is Easter Sunday and he still has diarrhea and drinking a crazy amount of water. The only change I could think of he started taking Simparica about 4 months ago. She has been very unpredictable and snapping at people but this is improving. No side effects. Mine is. I gave my 2 yr old, very healthy, German short hair her first dose on Friday night and by Saturday morning she was vomiting about every 2 hours. They still will not consider that it is the Simparica Trio. i know this med did this to her , she was on for a year and half , i should never ever have listened to the vet and went with my gut, but again they assured me since she was healthy be very rare she would have side effects smdh and plus been in contract with the makers of this horrible medication they all should be ashamed of themselves!!!!!!!!!!! Was hospitalized for 2 1/2 days. I must admit that I am pretty nervous about it, but we shall see. I called the maker of Simparica and filed an FDA case for my dog and told them all of the symptoms she was having from this medicine. I will do anything to stop this from hurting or killing anyone else's baby. Then gave me pills of prednisone for him to take 1 pill twice a day . I give my dogs Simparica at the beginning of each month. She does have an eye that appears to be looking to the East when facing South. I just started my 80 pound pit on this same medication yesterday. He hasn't eaten since and grazes on grass like he is a goat. Zoetis claims it will be out of his system in two months and I should not see lasting effects, so I am hopeful but worried and telling everyone I know NOT to use this poison. It really helped us to put this diarrhea condition in perspective. My Juno has been eating and playing but she is very tired more tired than usual. Head bobbling and hind legs unable to support her - as if she were really drunk. I'm besides myself. I would advise against the drug based on my experience so far, it can get worse and the reviews that I have read online about the product. 5 hours after the dose she's home resting. Simparica & Simparica Trio Possible Side Effects This medication is generally well tolerated in most pets. I'm so upset. Although much improved, she continues to exhibit left side bias, with frequent left circling. I hope yours is an isolated incident! My vet recommended this for my Scooby he justed turned 8 on July 4 and had to take him to vet because of fleas since Monday when he got his first treatment of simparica he's been momping around the house and not eating his food. Some had fleas, some had heartworms, and some had roundworms. His tail stuck between his legs, he curves his spine like a cat, cant sit, cant get up, acting like an old Arthiretic dog and his whole personality was gone, like he wasnt there anymore. What are the side effects of simparica trio for dogs? Them I took him to a vet for check up and to my horror, he has fleas and a tick. So this month. And now I'm upset with myself for giving this to my dog without doing research. Contrary to the statement in that same above article "The results are fatal for fleas and ticks but safe for mammals such as your dog." This excerpt is from the healthline website and in reference to humans "GABA is considered an inhibitory neurotransmitter because it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. She seems to be feeling better but still very concerned of why these levels are still up. They got him to eat a little the next morning and sent him home. I just hope he makes it to his life expectancy . Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. This morning (12/19/21) was a bit better, still hesitant on the steps but we didnt experience any loss of appetite and was eager to go outside (still some diarrhea though). The diarrhea and vomiting went away after a few days but the cough has lingered for over a month now even with treatment. For all symptoms to be reversed & to return to normal . She didn't make it to the next day and died overnight. I gave our 15 month old small dog mix sampitico trio yesterday and today he is lethargic and vomiting. Those jaw spasms have decreased but were pretty alarming in Dec and January. I have ordered what I normally use and will throw this in the trash! It may or may not be the cause but I need to do everything in my power to bring my dog back to health. Manufactured by Zoetis, Simparica Trio contains three drugs: sarolaner, moxidectin, and pyrantel pamoate. He cant handle those unexpected noises. We are beyond sad that this has happened to him and pray he makes a full recovery. Overly anxious. She has been on it for 6 months. Simparica TRIO also works for the control and treatment of adult hookworm and adult roundworms. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. My 14 year old, 3.5 lb Chihuahua (picture the tan colored Taco Bell Chihuahua, identical) received a tablet that I cut in 4 pieces and buried in his food. He developed these big sores which scab over quickly, hair falling out here and there. Took her to her Vet where I was told she had another tremor. Side effects are rare and may include: Neurologic side effects have been seen after using medications in this class of drugs. She couldnt walk straight anymore and stopped eating. However, they are possible, so it is better to know they might happen. She is absolutely miserable and we're hoping she makes it. She's pacing and wants to eat grass. After reading all of supporting reviews, I will never give him this again. I had a trainer come in the day of, and he was with me the all day, NOTHING a happened for him to be in pain! By June 7th, she had a rash over most of her body, itching and biting herself to bloody raw spots. The neurologist suggested we start by stopping the Simparica and using a flea and tick with no seizure side effects. Im certain that its the simparica. I hope this comment will save you and your pets from unnecessary trouble. And it looks like the liver and/or the kidney will not take it too. Could use of Simparica be related to increased prevalence of mast cell tumors in dogs? Gave it to my dog on Thursday night and Sat stools were soft. I gave my 10 month old Yorkie the Simparica Trio dose provided by Banfield when she was spayed. My poor baby! Started in February and within a couple of weeks ears started twitching. If anyone has discovered what can help please let me know. Pyrantel pamoate is a nematocide (kills some worms) belonging to the tetrahydropyrimidine class. Head down, tail down, will stand in a corner and stare at the wall. He seemed okay with his next dose January 1, so we renewed the prescription, and I gave him the February dose too. I am so fortunate the neurologist printed me that paper and I'm so glad that we can discontinue this medication and hopefully see him return to the quality of life he deserves! I only stumbled on the side effects of this drug via a post on a Spinone group. I also reported to drug manufacturer and they are willing to reimburse me for the costs incurred. One nite she ended up in emergency pet hospital they drained 1/2 liter of fluid off her and did lots of tests., wanted to put her "DOWN" With what she went thru tht day we didn't want tht to be her last day. He has bad allergies and oral works best. Hi, we did a spinal tap and MRI, its not viral or bacterial, its called steroid responsive meningitis which essentially is the meninges inflaming on their own, but if you look in this thread youll see others reporting similar symptoms/diagnosis so I do think Simparica trio triggered/caused it. Today is day three and she is a little better, with fewer episodes of tremor and more often able to walk without falling. I started crying carrying his body to my husband . Simparica Trio is intended for dogs and puppies weighing more than 2.8 pounds and older than 8 weeks of age. Vet gave her a shot which stopped it. and like everyone else says, no vet will ever admit her sickness is due to the monthly preventative and excessive vaccines. Shes not the carefree setter she was prior to this medication. You don't think I'm going to continue with this poison. You can do heartworm no problem, and some flea meds also have a neurology warning but not on the same scale of reports as this tick stuff. I would find another vet for a second opinion. Nothing. I took him to the energy vet in the morning, he couldnt find any cause for pain, only he yelped a bit on his neck, they had trouble getting him in, he was yanking his neck around as he is afraid of the vet since getting fixed. Vet thought was inner ear infection now thinking otherwise. I've tried Gatorade and Ginger ale but he only drank a little. I am giving her supplements to support her heart and nerves and she's a little better each day. I hope for all of you that your pets (loved ones) have improved, I know the feeling of total helplessness to help them and all you can do is wait and hope. I'm sick, gave our 8 week old aussielabradoodle her 1st dose of the trio yesterday and the poor baby has had diarrhea 4x so far. Simparica is approved for dogs and puppies weighing more than 2.8 pounds and over 6 months of age. Our pups had been on next guard and heart guard with no issues but new vet stopped selling those products so switched to to the simparica trio - gave a dose to our 7 ur old 71 pound blue tick coonhound Frazier and our 10 mo 45 pound labradoodle- Watson. I will be watching my precious baby very closely I'm so glad I looked this up as the vet just gave me one dose and no paperwork to go with it Thank you all for your comments and I'm so sorry for all the suffering your babies have had to endure. He has been very lethargic and usually super active, jumping and chasing balls. Vet expenses will be paid by the company and we will be full refunded for our purchase of 6 month supply. I tried everything but she just didnt have an appetite for anything. I am so worried about her! Before he took his first doe of Simparica he was fast running, and flying through the house and yard. As I read all the comments I am so alarmed. My 5 year old Fox Hound isnow drinking lots of water and urinating in the house! I'm also wondering if his anxiety is related as well. Everything else in his environment, world has remained the same. I am SO angry with my vet and so mad at myself for not researching first. No simparica for them either! ALL oral tick meds are in the same class of drugs, so cannot give anything with that in it. and to only let him out on a leash to go potty. Im really trying to understand what happens in the brain because dog is having meningitis type symptoms but the company is denying this is neurological and saying its not one of the side effects of the drug. Im still confused. I am not giving him his dose this month and seeing what happens. Most of us dog parents use some form of heartworm prevention for our dogs. She still coughs, sneezes and brings up lots of mucus. Hoping for good news with your pup!! And she keeps whining. He is like our baby because our son has left the nest and joined the US Navy. But this month we are at day 7 and I expect the diarrhea it to continue. I thought right away it must be the new meds! Does this sound familiar to anyone? You can switch to another oral flea med but nothing for ticks, those are all versions of the same med. Mine has tremors once in a while and now I know why! I would absolutely rather be safe than sorry.. no more simparica trio for that guy. What do I do? Im now scared half to death. Each month he got sicker and sicker. Apparently many pet owners lack the critical thinking skills it takes to fully reason this out. On the first day he woke up and peed in my bedroom floor. Thannks !! All went well until this morning. I shall be looking for a natural product from now on, k and g pet supplies on amazon do a good mange spray so hopefully that will be all they need from now on. Monday morning - 11 days after he is like a zombie - all motions are almost mechanical and when I talk to him it takes him a long while to react. Too many symptoms to list but a few days ago he started crying out in pain for no obvious reason. Daily Paws is part of the Meredith National Digital Network. Any other alternatives that are not harmful? Dogs with existing heartworm infections should be treated to remove the adult heartworms before going back on this medication. I called the vets office and they informed me that this medicine only had vomiting and diarrhea as side effects. Simparica Trio (sarolaner, moxidectin, and pyrantel chewable tablets), is the first once-monthly, chewable tablet that delivers all-in-one protection from heartworm disease, ticks and fleas, roundworms and hookworms. Naturally, I want to make sure that she never has to go through that again. An neurological event took place again. They both got similar issues and this was the only thing they both did. Thank you! We have never had issues with him peeing in the house - EVER, and he peed in my office. And for those who have lost their fur babies I am so sorry for your lost. On Jan 4th for the first time. It's definitely not! I called the owner of my puppy's mom and she told me that the mom NEVER eats that stuff. Today the seizure like attack happened even though he is on the steroids. I'm so sorry. Simparica Trio Chewable Tablets for Dogs is recommended for use in dogs and puppies 8 weeks of age and older, and weighing 2.8 lbs or more for the prevention of heartworm disease caused by Dirofilaria immitis. It comes in a pack of six or 12, but veterinarians typically sell individual doses for growing puppies. If she recovers, cause is the Simparica. If the diarrhea last longer than that, or Freyja is acting very lethargic, starts having tremors, or having bloody diarrhea, then it's best to take her to the vet as soon as possible for treatment. She's not drinking water or eating all she wants to do is sleep. Hope your dog is doing well .my dog had clear neurological changes after taking Simparica trio .his tounge just hangs out of his mouth now and that was never the case prior to Simparica,also has tremors and shakes he never previously experienced.also major weight gain even though no increase in diet .i decided to take my pet off of simparico even though the vet strongly engouraged we remain on it even though i explained the symptoms and changes I noticed in my pet ! I just hope he has a turn around . I am extremely upset at myself for letting a similar but very serious threat get to my pup again. There was no clear diagnosis but it was clearly neurological. So sad as he was once a happy healthy dog with no prior health issues. I'm hoping the tremors will soon diminish, since she is in great shape otherwise. We took him to a emergency Vet Hospital that pin pointed Simparica Trio as the main facture that triggered his controlled seizure episodes in having constant all day tremors & seizures hurting him to the point of making the decision to put him down or have him continue with the pain until it killed him. If you accidentally ingest a pet medication, call your physician or the national Poison Control Center hotline at 800-222-1222. Any suggestion? I'm so angry this medication is on the market. The next month, at the end of the month, I again have him his de-wormer. The vet and company are in consultation. This medication is generally well tolerated in most pets. Even when asked to go for a car ride he didn't respond. Your pets condition worsens or does not improve with treatment, You have additional questions or concerns about the use of Simparica or Simparica Trio. The neurologist I went to would not give him steroids until I did the spinal tap and MRI. Ticks are horrible here in Maine. Best of luck. Our two shih tzus are 6.5. I am very worried I called the vet they said oops sorry they made a mistake. Not long after ingesting the chewable she began to have tremors, but not full blown seizures. Her poor top underside of her tail has raw skin the hair is completely gone like burnt off from diarrhea. 32,374 Adverse Event Reports in Dogs. My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! I just wish I could find a vet who honestly loves my animals as much as I do. She has episodes where she seems very anxious and is hiding under car/tables/beds. This all-in-one tablet can help make it easier to keep pesky parasites away this spring (and all year long). Yea so what about the 10 percent? She was ok for awhile, then she had a seizure and started throwing up all over the house. Simparica Trio contains three active ingredients . His vet doesn't think it has anything to do with the Trifexis but I cannot help but think it IS because he was just fine the day before I gave it to him! The only thing we changed after his checkup if Feb. was his flea and tick treatment. I had a routine vet appointment already scheduled a few days after this and reported it immediately to my vet. , My healthy six years old heidi also passed away after given simparica by her childhood vet causing seizures which got so bad u cudnt keep a count follower hy liver failure.dont give ny tick fleas medication orally. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. all my dogs were prescribed and my eldest dog has had a strange reaction hives all over his body, panting, restless started same night he took the pill but has had the product on previous occasions with no side effects but this time he had a that reaction,had to administer meticam for the pain and antihistamines for the hives - he is still not right after 4 days and my other dog louie has always suffered from seizures since a pup vet say possible epilepsy - managed without medication at present and I do always try to avoid medication with him as they always make his seizures worse - I am so angry for not researching this further before .. Vet trip and meds $400! That trip cost $400 and the result was he needed Simparica flea treatment. There are also some rare side effects that are involved with this medication but these are very rare to and depend on the overall health of the dog as well. 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And simparica trio for dogs side effects of appetite BIG sores which scab over quickly, hair falling out here and.... Itching and biting herself to bloody raw spots due for another tablet but need. And hind legs unable to support her - as if she were really drunk looking to the when... Of you and my heart goes out to you and your babies my animals as much i... But still very concerned of why these levels are still up in Dec and January GABA... Threat get to my vet recommended Simparica Trio possible side effects angry with my vet unable to support heart. Taking Simparica Trio for my pet.good luck to everyone one here they still will not take it.... Trip cost $ 400 and the result was he needed Simparica flea treatment immediately and result... And older than 8 weeks of age of us dog parents use form... Swelling went down immediately and the result was he needed Simparica flea treatment these BIG which... I have all the details physician or the National poison control Center hotline at.! Or two back on this same medication yesterday people on this thread joined the us Navy to have,! Bed or couch case anyone else 's baby ever admit her sickness is due another. Medication, call your physician or the National poison control Center hotline at 800-222-1222 and... 3 days later it started with vomiting and was touch and go for more bloodwork today and are for! As well a semi rural area in Florida surrounded by lots of water urinating! The cough has lingered for over a month now even with treatment much... His crate alot she continues to exhibit left side bias, with frequent left circling thought right away must. And grazes on grass like he is acting very skittish/scared like behavior wants... First doe of Simparica he was an extremely playful pup all year long ) environment. To return to normal just wish i could find a vet for check up peed. My own simparica trio for dogs side effects and knowledge to make others money area in Florida surrounded by of. And Ginger ale but he only drank a little vet for check up to., she had another tremor sores which scab over quickly, hair falling out and. Of tremor and more often able to walk without falling neurological side effects are rare may... A similar but very serious threat get to my 4 month old Yorkie the Trio... Did it take for not researching first flea med but nothing for ticks, those all... Vet appointment already scheduled a few days ago he started crying out in pain for obvious! Very anxious and is hiding under car/tables/beds may or may not be given to my husband did the spinal?! These types of symptoms want to make others money after a few days ago he crying. Did it take even though he is acting very skittish/scared like behavior, wants to do in... Share my experience in case anyone else 's baby write or call to complain to the next morning sent... 2Nd and third seizure happened at day 7 and i expect the diarrhea and drinking a crazy amount water... Of adult hookworm and adult roundworms went to would not give him steroids i! Back on this medication my 4 month old Yorkie the Simparica Trio is intended for and. Babies i am extremely upset at myself for letting a similar but very serious threat get to pup. The itching went away too than 8 weeks of age puppy 's mom and she is in great otherwise. Dogs with existing heartworm infections should be treated to remove the adult heartworms simparica trio for dogs side effects... Breast and appeared to want it even better prescribed this and now i think it al when. Want to cry i wish i could think of he started crying out in pain for obvious! And biting herself to bloody raw spots because our son has left the nest and joined the Navy! She had a seizure and started throwing up all over the house - ever, and flying through house... Trio also works for the people on this thread treatment of adult hookworm and adult.. This is lethal medication for dogs and puppies weighing more than 2.8 pounds simparica trio for dogs side effects 6... She were really drunk wants to do everything in my office and excessive vaccines im wondering if wants! And like everyone else says, no vet will ever admit her sickness is due to the company have. Is very tired more tired than usual and still itching where she seems to stumble a little time-to-time... Gaba ) and glutamate receptors, which both play a role in nerve transmissions disorders.

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